Names:                                         :
Confidence, Significance and P-Values
Work in groups of 2 or 3 (turn in only one paper per group). We will learn how to do significance tests with the TI-83 calculators in this activity. We start with an example done by hand.
  1. Acute myeloblastic leukemia is among the most deadly of cancers. Experience indicates that the time in months that a patient survives after initial diagnosis of the disease is normally distributed with a mean of 13.0 months and a standard deviation of 3 months. A new treatment is being investigated that should prolong the average survival time without affecting the variability. The survival times for 16 patients receiving the new treatment are listed below.
17.8 12.5 16.7 17.3 12.5 18.3 10.5 13.3
21.4 16.2 10.3 11.8 8.8 13.2 12.5 15.6
  1. Set up a significance test for the information above by defining the null hypothesis H0 and the alternative hypothesis Ha.

  2.  

     
     
     
     
     
     
     
     

  3. Calculate the mean, , of the sixteen survival times.

  4.  

     




     
     

  5. Using the fact that the population standard deviation is equal to 3, what is the standard deviation of the sampling distribution for  (assuming the null hypothesis is true)?

  6.  

     
     




     
     

  7. Calculate the p-value of your significance test for the observed value of .

  8.  

     
     




     
     
     

  9. Based on your p-value, do you think that the observed value of  would lie in a 95% confidence interval (for the statistic  = mean of 16 survival times) centered at the population mean µ = 13? Explain.

  10.  

     
     





     
     
     

  11. Find a 95% confidence interval centered at 13 for the statistic . Using the Z-Interval command, set s = 3 (the population standard deviation)  = 13, n = 16 and C-Level = .95. Is the observed value of  in this interval?





 

Now we'll repeat the significance test above with some new features of the TI-83. Most likely you already calculated the values of  using the 1-VarStats feature of your calculator (so the data is already in L1). Be sure that the 16 times are stored in the list L1 and delete or turn off all Y-variable plots and STAT plots. We can calculate the p-value of a significance or hypothesis test quite quickly with the TI-83. This can be done either with data (such as the list of survival times), or with statistics (the values of x-bar and n = the sample size). For both methods you'll need to know the population mean, µ, and the population standard deviation, s. Press [STAT] and then select the [TESTS] submenu. Hypothesis tests (of this type anyway) are called Z-Tests on the TI-83 and they correspond to the first choice on the [TESTS] submenu. Select 1:Z-TEST. The hypothesis test editor screen should appear. You move around with the arrow keys and make selections by pressing [ENTER]. Select DATA for the input type. Enter the population mean (13) for µ0 and the population standard deviation (3) for s. Give L1 as the list and set the frequency to 1. The second to last line is where you select the form of the test. You can chose from

a two tailed test 
a left tailed test 
or a right tailed test 
Select the right tail test icon and then select DRAW on the bottom line to see a plot and the p-value. The calculator plots the standardized version of the problem and reports the standardized z-value as well.


What is the z-value reported?
 
 
 

Did you get the same p-value as above?
 
 
 

Now, go back to the Z-Test screen and select STATS this time for the input type. The calculator should display the screen below.

The values from your last test should remain in the Z-Test editor. Move to the bottom line and select Calculate this time. You should get the same p-value and the same Z-value as before, just no graph this time. The calculate option is nice if you only need a number for the p-value or z-value. Here is one more example to try out using the new commands.
 
  1. Under normal conditions, annual growths of a certain type of tree are known to be normally distributed with a mean of 11 inches of growth per year and a standard deviation of 2.3 inches. An experimental insecticide is used on a sample of 48 of these trees, and the researcher is interested in seeing if the insecticide has any effect on the annual growth of the trees.
    1. Does this setting call for a right-tailed test, left-tailed test or two-tailed test? Why?

    2.  

       
       
       
       






       
       
       
       

    3. Define the appropriate null and alternative hypothesis for this significance test.

    4.  

       
       
       
       
       
       
       
       
       

    5. The researcher finds that with the insecticide, the 48 trees grew an average of 10.3 inches. Assume the insecticide has no effect on the standard deviation of these growths. Draw a graph that illustrates the p-value (as an area under a normal density curve) and report the p-value of this test.

    6.  

       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       

    7. Explain in everyday language, how confident you are that the insectide did or did not affect the tree's growth.

    8.